Big-box commercial jumble, lifeless cul-de-sac subdivisions, urban sprawl, deteriorated downtowns, and traffic jams aren’t just sickening sites, but literally may be making Americans sick.  There is a growing body of evidence that suggests how places are designed and built can cause and complicate grave health problems for individuals and whole populations.  This article illustrates examples of how strategies such as New Urbanism and health-focused design solutions can promote walkability, mixed use, connectivity and civic space within communities.